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Sophia Yin MS, DVM
This segment is excerpted from material published in “Low Stress Handling, Restraint and Behavior Modification of Dogs & Cats” by Sophia Yin, DVM MS, with permission of the author.  The book can be purchased at this link.

This video illustrates some counterconditioning techniques to use with cats to help with administering pills.  You can start by gently restraining the head, and giving treats.  Repeat this approach until the cat equates having her mouth open with receiving treats.

You can then use the same technique to give a pill, followed immediately with a treat.